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Vaccine Could Prevent and Treat Precancerous Breast Lesions

2/6/17 8:54 AM

As the search for a cure to breast cancer continues, doctors at the Mayo Clinic have developed a vaccine they hope will treat and prevent precancerous breast lesions. According to the nonprofit, only 35% of precancerous breast lesions can morph into cancer if untreated.

One of those lesions, ductal carcinoma in situ, accounts for about 20% of breast cancer cases in the United States. Unfortunately, there's no way for doctors to know which lesions could turn potentially dangerous.

Dr. Knutson, who designed the vaccine says, "We ultimately want to eliminate ductal carcinoma in situ, which means preventing disfiguring surgeries and toxic therapies in the 60,000 women who receive this diagnosis every year in the U.S."

Testing for the vaccine is scheduled to begin in four months on 40-45 patients diagnosed with ductal carcinoma in situ. Patients will first be treated with the vaccine, then six weeks later will undergo surgery and other therapy treatments. During that time, the patients will be monitored to see if the ductal carcinoma in situ lesions react to the vaccine.

The vaccine was designed to prevent the recurrence of triple-negative breast cancer, which there are currently no treatments for. In phase I clinical studies, the vaccine was found to be safe for targeting the development of an aggressive subtype of breast cancer known as HER-2 and ductal carcinoma in situ.

Hope is that the phase II clinical trial will show that the vaccine will cause the lesions to disappear. If successful, the vaccine could act as a substitute for painful surgeries and radiation treatments. There's even talk that it could one day become a routine immunization for healthy women.

One important aspect of ensuring the safety and effectiveness of vaccines is ensuring they are stored at proper temperatures at all times. To help comply with the strict regulations set by the CDC, MadgeTech offers the Vaccine Temperature Monitoring System. To view the complete guide for continuous vaccine temperature monitoring, click here.

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MadgeTech Marketing Team